Progressive retinal atrophy (PRA)
Description
Progressive retinal atrophy (PRA) is a group of conditions in which the retina degenerates. The breeding programmes approved by DWV check for PRA in two ways. With a DNA test, from birth and once, for a form of PRA with a known variant, for example progressive rod-cone degeneration (Prcd-PRA) or cone-rod dystrophy 4 (cord1-PRA/crd4). Which form is tested for a breed is set out in the breeding programme; Prcd-PRA is mandatory for the Labrador Retriever and the Golden Retriever, for example. Through the general eye examination, under the name retinal degeneration (PRA). There the breeding advice is positive for clear with clear, conditionally positive for clear with suspect, and the other combinations are subject to a breeding ban.
Inheritance pattern
Autosomal recessive, according to the breeding programme. A carrier has a 50% chance of passing the variant on to its offspring; an affected dog passes it on to all its offspring. In most breeding programmes the breeding advice is positive when at least one parent dog is clear; the other combinations are subject to a breeding ban.
Breeds in which this condition occurs
We are rebuilding the health information for each breed from the official breeding programme of Dierenwelzijn Vlaanderen (Animal Welfare Flanders). Until then, you can find the mandatory and recommended health tests for this breed in the breeding programmes under the Flemish Breeding Decree (Fokkerijbesluit). View the official breeding programmes
